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KMID : 0604520090350040277
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Journal of the Society of Cosmetic Scientists of Korea
2009 Volume.35 No. 4 p.277 ~ p.285
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Anti-inflammatory Effects of Prescription Extracts Containing Forsythia viridissima L
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Kim Mi-Jin
Lim Kyung-Ran
Yoon Kyung-Sup
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Abstract
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Forsythia fructus has been shown to have antioxidative, anti-inflammatory, antiviral, antitumor, antibacterial, antipyretic and anti-aging activities. This work was carried out to investigate the anti-inflammatory effects of the Korean traditional medicinal prescriptions containing Forsythia viridissima extract. The prescriptions containing Forsythia fructus were evaluated for antioxidative effects, inhibitory effects on lipoxygenase activity and on LPS-induced NO and production. In human irritation test, they did not show any adverse effect. Based on these results, we suggest that the se prescriptions hold great promise for application as an anti-inflammatory agent for trouble skins such as atopic dermatitis and acne.
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KEYWORD
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prescription extracts containing Forsythia viridissima, anti-inflammatory effect, antioxidative effect, protaglandin , nitric oxide
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